Maternal hyperglycemia induces alterations in hepatic amino acid, glucose and lipid metabolism of neonatal offspring: Multi-omics insights from a diabetic pig model.
Shashikadze, Bachuki; Valla, Libera; Lombardo, Salvo Danilo; Prehn, Cornelia; Haid, Mark; Riols, Fabien; Stöckl, Jan Bernd; Elkhateib, Radwa; Renner, Simone; Rathkolb, Birgit; Menche, Jörg; Hrab? de Angelis, Martin; Wolf, Eckhard; Kemter, Elisabeth; Fröhlich, Thomas
Particle fusion of super-resolution data reveals the unit structure of Nup96 in Nuclear Pore Complex.
Wang, Wenxiu; Jakobi, Arjen; Wu, Yu-Le; Ries, Jonas; Stallinga, Sjoerd; Rieger, Bernd
ModelRevelator: Fast phylogenetic model estimation via deep learning.
Burgstaller-Muehlbacher, Sebastian; Crotty, Stephen M; Schmidt, Heiko A; Reden, Franziska; Drucks, Tamara; von Haeseler, Arndt
Studies of proline conformational dynamics in IDPs by 13C-detected cross-correlated NMR relaxation
Schiavina, Marco; Konrat, Ruth; Ceccolini, Irene; Mateos, Borja; Konrat, Robert; Felli, Isabella C; Pierattelli, Roberta
Mutational landscape of intestinal crypt cells after long-term in vivo exposure to high fat diet.
Meyenberg, Mathilde; Hakobyan, Anna; Papac-Milicevic, Nikolina; Göderle, Laura; Langner, Franziska L; Markovic, Mateo; Lee, Ji-Hyun; Koo, Bon-Kyoung; Busslinger, Georg A; da Silva, Israel Tojal; Binder, Christoph J; Menche, Jörg; Loizou, Joanna I
AutoCore: A network-based definition of the core module of human autoimmunity and autoinflammation.
Guthrie, Julia; Köstel Bal, Sevgi; Lombardo, Salvo Danilo; Müller, Felix; Sin, Celine; Hütter, Christiane V R; Menche, Jörg; Boztug, Kaan
Proteomics and disease network associations evaluation of environmentally relevant Bisphenol A concentrations in a human 3D neural stem cell model.
Horánszky, Alex; Shashikadze, Bachuki; Elkhateib, Radwa; Lombardo, Salvo Danilo; Lamberto, Federica; Zana, Melinda; Menche, Jörg; Fröhlich, Thomas; Dinnyés, András
piRNA processing by a trimeric Schlafen-domain nuclease.
Podvalnaya, Nadezda; Bronkhorst, Alfred W; Lichtenberger, Raffael; Hellmann, Svenja; Nischwitz, Emily; Falk, Torben; Karaulanov, Emil; Butter, Falk; Falk, Sebastian; Ketting, René F
TERRA expression is regulated by the telomere-binding proteins POT-1 and POT-2 in Caenorhabditis elegans.
Manzato, Caterina; Larini, Luca; Pegorar, Claudio Oss; Dello Stritto, Maria Rosaria; Jurikova, Katarina; Jantsch, Verena; Cusanelli, Emilio
Damaged mitochondria recruit the effector NEMO to activate NF-?B signaling.
Harding, Olivia; Holzer, Elisabeth; Riley, Julia F; Martens, Sascha; Holzbaur, Erika L F
Increased alpha-synuclein and neuroinflammation in the substantia nigra triggered by systemic inflammation are reversed by targeted inhibition of the receptor for advanced glycation end products (RAGE).
Peixoto, Daniel Oppermann; Bittencourt, Reykla Ramon; Gasparotto, Juciano; Kessler, Flávio Gabriel Carazza; Brum, Pedro Ozorio; Somensi, Nauana; Girardi, Carolina Saibro; Dos Santos da Silva, Lucas; Outeiro, Tiago Fleming; Moreira, José Cláudio Fonseca; Gelain, Daniel Pens
Inhibition of adenovirus replication by CRISPR-Cas9-mediated targeting of the viral E1A gene
Zrinka Didara, Florian Reithofer, Karina Zöttl, Alexander Jürets, Izabella Kiss, Angela Witte, Reinhard Klein
SPOP targets the immune transcription factor IRF1 for proteasomal degradation.
Schwartz, Irene; Vunjak, Milica; Budroni, Valentina; Cantoran García, Adriana; Mastrovito, Marialaura; Soderholm, Adrian; Hinterndorfer, Matthias; de Almeida, Melanie; Hacker, Kathrin; Wang, Jingkui; Froussios, Kimon; Jude, Julian; Decker, Thomas; Zuber, Johannes; Versteeg, Gijs A
Loss of LCMT1 and biased protein phosphatase 2A heterotrimerization drive prostate cancer progression and therapy resistance.
Rasool, Reyaz Ur; O'Connor, Caitlin M; Das, Chandan Kanta; Alhusayan, Mohammed; Verma, Brijesh Kumar; Islam, Sehbanul; Frohner, Ingrid E; Deng, Qu; Mitchell-Velasquez, Erick; Sangodkar, Jaya; Ahmed, Aqila; Linauer, Sarah; Mudrak, Ingrid; Rainey, Jessica; Zawacki, Kaitlin P; Suhan, Tahra K; Callahan, Catherine G; Rebernick, Ryan; Natesan, Ramakrishnan; Siddiqui, Javed; Sauter, Guido; Thomas, Dafydd; Wang, Shaomeng; Taylor, Derek J; Simon, Ronald; Cieslik, Marcin; Chinnaiyan, Arul M; Busino, Luca; Ogris, Egon; Narla, Goutham; Asangani, Irfan A
p62 and NBR1 functions are dispensable for aggrephagy in mouse ESCs and ESC-derived neurons.
Trapannone, Riccardo; Romanov, Julia; Martens, Sascha
Lipid saturation controls nuclear envelope function.
Romanauska, Anete; Köhler, Alwin
Structural evidence for elastic tethers connecting separating chromosomes in crane-fly spermatocytes.
Forer, Arthur; Otsuka, Shotaro
Enhancers of the PAIR4 regulatory module promote distal VH gene recombination at the Igh locus
Louisa Hill, Markus Jaritz, Hiromi Tagoh, Karina Schindler, Daniela Kostanova-Poliakova, Qiong Sun, Tanja A Schwickert, Martin Leeb, Meinrad Busslinger
A phylogenetic profiling approach identifies novel ciliogenesis genes in Drosophila and C. elegans
Jeroen Dobbelaere, Tiffany Y Su, Balazs Erdi, Alexander Schleiffer, Alexander Dammermann
A critical evaluation of protein kinase regulation by activation loop autophosphorylation.
Reinhardt, Ronja; Leonard, Thomas A
Phage therapy for treating bacterial infections: a double-edged sword
Suckers and segments of the octopus arm
Using the house mouse radiation to study the rapid evolution of genes and genetic processes
CRISPR jumps ahead: mechanistic insights into CRISPR-associated transposons
SLiMs and SHelMs: Decoding how short linear and helical motifs direct PPP specificity to direct signaling
Title to be announced
Enigmatic evolutionary origin and multipotency of the neural crest cells - major drivers of vertebrate evolution
Visualising mitotic chromosomes and nuclear dynamics by correlative light and electron microscopy
Engineered nanocarriers for imaging of small proteins by CryoEM
Bacterial cell envelope homeostasis at the (post)transcriptional level
Title to be announced
Hydrologic extremes alter mechanisms and pathways of carbon export from mountainous floodplain soils
Dissecting post-transcriptional gene expression regulation in humans and viruses
Prdm9 control of meiotic synapsis of homologs in intersubspecific hybrids
Polyploidy and rediploidisation in stressful times
Title to be announced
RNA virus from museum specimens
Programmed DNA double-strand breaks during meiosis: Mechanism and evolution
Title to be announced